Chirality from Dynamic Kinetic Resolution PDF
By:Hélène Pellissier
Published on 2011 by Royal Society of Chemistry
The last 15 years have witnessed significant developments in the efficiency and scope of the application of DKR. These now offer a serious alternative to conventional methods for asymmetric synthesis. Indeed, impressive examples using new enzymes and major progress in the DKR of racemates have taken place over the past few years. The powerful combination of enzymes and metals has also been the subject of spectacular development. In addition, a new type of DKR, involving organocatalysts, has recently appeared. Although asymmetric catalysis has undergone development during the last two decades, the most common industrial process used to obtain enantiomerically pure compounds is still via resolution of racemic mixtures. This is despite the major disadvantage that only a maximum of 50% product yield can be obtained. It is not surprising that DKR, which solves the problem of the limitation in yield, has attracted an increasing amount of interest from both the industrial and the academic perspective. This book provides an up-date on the principle methods employed to obtain dynamic kinetic resolution (DKR) by either enzymatic or non-enzymatic methods. It also illustrates the diversity of useful chiral products that can be obtained through this powerful concept. Divided into three sections, the book deals successively with non-enzymatic methods, enzymatic methods, and the use of transition metals and enzymes in tandem.
This Book was ranked at 36 by Google Books for keyword Resolution.
Book ID of Chirality from Dynamic Kinetic Resolution's Books is vn2DesW1KBgC, Book which was written byHélène Pellissierhave ETAG "aXfmfU31Mx0"
Book which was published by Royal Society of Chemistry since 2011 have ISBNs, ISBN 13 Code is 9781849731973 and ISBN 10 Code is 1849731977
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Book which have "299 Pages" is Printed at BOOK under CategoryScience
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